Synthesis and evaluation of flavonols showed potential as dual enzyme inhibitors for tyrosinase and pancreatic lipase, suggesting therapeutic benefits.
Aims Tyrosinase and pancreatic lipase are key enzymes involved in melanin biosynthesis and lipid metabolism, respectively. Their inhibition offers therapeutic potential in treating hyperpigmentation and obesity. This study aimed to synthesize and evaluate a series of flavonols (1–10) as potential dual enzyme inhibitors.
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Mughal et al. (2025) studied this question.
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