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September 5, 2025World NeurosurgeryOpen Access

Quantitative Susceptibility Mapping in the Assessment of Single and Repeated Closed Mild Traumatic Brain Injury

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Authors

YYYishan YaoWZWenbing ZhaoCLChang Li

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Overview

This study analyzes changes in magnetic susceptibility in brain tissue after repeated mild traumatic brain injury, indicating significant neurobiochemical alterations.

Key Points

  • Repeated mTBI causes greater neurological deficits than single mTBI, lasting for 8 weeks.
  • Changes in magnetic susceptibility were more pronounced in the chronic stages after repeated mTBI.
  • Quantitative susceptibility mapping successfully detects neurobiochemical changes related to mTBI.
  • Fluorescence staining highlighted glial proliferation and Tau protein deposition following mTBI.

Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef02b87ece8dc9575c9https://doi.org/10.1016/j.wneu.2025.124413
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