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September 5, 2025Surgical EndoscopyOpen Access

Changes in peristalsis following per oral endoscopic myotomy in common esophageal motility disorders

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Authors

SVSameer VyasPost Graduate Institute of Medical Education and ResearchMWMarc A. WardBaylor University Medical CenterBBBrittany BuckmasterBaylor University Medical Center

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Overview

Observational analysis reveals peristalsis recovery in Type 1 and 2 achalasia post-POEM, indicating varied outcomes for different conditions.

Key Points

  • Type 1 achalasia saw the most significant improvement in peristalsis, with 45.5% of patients achieving restoration after POEM.
  • Esophagogastric junction outflow obstruction exhibited the poorest outcomes, showing severe peristalsis loss and a drop in DCI.
  • Jackhammer esophagus patients experienced a return to normal DCI levels after POEM, with variable peristalsis recovery.
  • Type 3 achalasia had a decrease in peristalsis from 82.5% pre-operative to 64.5% post-operative, indicating complications post-POEM.

Cite This Study

Vyas et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef02b87ece8dc9575fbhttps://doi.org/10.1007/s00464-025-12096-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Peroral endoscopic myotomy and its use in non-achalasia disorders2024 · 3 citations
  2. 2Achalasia: laparoscopic Heller myotomy with fundoplication versus peroral endoscopic myotomy—a systematic review and meta-analysis2024 · 22 citations
  3. 3The Chicago Classification of esophageal motility disorders, v3.02014 · 1,972 citations
  4. 4Long‐term outcomes of treatment for achalasia: Laparoscopic Heller myotomy versus POEM2024 · 14 citations
  5. 5Partial Recovery of Peristalsis After Myotomy for Achalasia2013 · 74 citations