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September 5, 2025CancerOpen Access

The legend of the response evaluation criteria in solid tumors: A historical overview

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Review examines historical development of response evaluation criteria in solid tumors, highlighting RECIST's evolution.

Current tumor response criteria trace back to a 1976 study, establishing pivotal metrics for evaluating treatment responses.
Key metric emerged from measuring a 50% reduction in tumor dimensions, later integrated into WHO criteria for progression.
Methodology critically evaluated includes historical approaches, transitioning from palpation to advanced imaging techniques.
Advancements warrant reassessment of criteria reliability, indicating a need for new methodologies in tumor response evaluation.

Smesseim et al. (2025) studied this question.

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