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September 5, 2025Molecules0 citationsOpen Access

Phytochemical and Anti-Helicobacter pylori Assessment of Haloxylon articulatum Extracts

Phytochemical Characterization and Anti-Helicobacter pylori Potential of Haloxylon articulatum Extracts: Antioxidant Activity and Molecular Docking Insights

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Authors

RAReyadh R. Al‐RashidiHNHana NasrallahABAmal Bouazzi

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Overview

Analysis shows beneficial antioxidant and anti-helicobacter pylori properties of haloxylon articulatum extracts, indicating potential for medicinal use.

Key Points

  • Root extracts of haloxylon articulatum displayed robust antioxidant activity and significant anti-helicobacter pylori effects.
  • Molecular docking demonstrated strong binding affinity of key compounds to bacterial isoleucyl-tRNA synthetase, with MICs of 54 ± 0.92 and 74 ± 1.05 µg/mL.
  • Phytochemical profiling identified 32 compounds, notably phenolamides and flavonoids, contributing to the plant's therapeutic potential.
  • ADMET predictions indicated the extracts have good oral bioavailability and low toxicity, supporting further preclinical evaluation.

Cite This Study

Al‐Rashidi et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef72b87ece8dc95785ehttps://doi.org/10.3390/molecules30173520
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