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September 5, 2025Journal of the American Geriatrics SocietyOpen Access

SCORE2‐Older Persons (SCORE2‐OP): Validation and Added Value of Excessive Daytime Sleepiness in a French Cohort

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Authors

TATahiana AndriambelosoaCCClémence CavaillèsJEJean‐Philippe Empana

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Overview

Observation reveals cardiovascular risk overestimation by SCORE2-OP in older adults, suggesting daytime sleepiness can enhance risk assessment.

Key Points

  • SCORE2-OP predicted 10-year cardiovascular risk was 14.04%, but observed cumulative incidence was only 10.55%.
  • Excessive daytime sleepiness significantly associated with cardiovascular events, showing adjusted hazard ratio of 1.32.
  • Adding daytime sleepiness to SCORE2-OP provided slight improvement in risk reclassification for men in certain risk groups.
  • Findings indicate SCORE2-OP overestimated risk in this cohort, highlighting need for improved preventive strategies.

Cite This Study

Andriambelosoa et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef72b87ece8dc9579edhttps://doi.org/10.1111/jgs.70047
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Systematic Coronary Risk Evaluation 2 for Older Persons: 10 years risk validation, clinical utility, and potential improvement2024 · 9 citations
  2. 2Validation of the European SCORE2 models in a Canadian primary care cohort2023 · 19 citations
  3. 3Cardiovascular risk estimation in older persons: SCORE O.P.2015 · 175 citations
  4. 4Performance of risk prediction scores for cardiovascular mortality in older persons: External validation of the SCORE OP and appraisal2020 · 8 citations
  5. 5Occupational and lifestyle factors associated with SCORE-2 cardiovascular risk among emergency healthcare workers2026