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September 5, 2025Journal of Interventional Epidemiology and Public HealthOpen Access

Seroprevalence of treponema pallidum in pregnant women at the time of delivery and their neonates at Misisi Mini-hospital and Chawama General Hospital, Zambia

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Authors

AHAgnes HambooteDBDabwitso BandaLMLwito Salifya Mutale

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Overview

This cross-sectional study estimates syphilis prevalence in pregnant women and their neonates, highlighting risk factors like HIV and vaginal discharge.

Key Points

  • Among pregnant women, 10% were diagnosed with syphilis at delivery, indicating a significant health concern.
  • 23% of neonates exposed to syphilis showed clinical signs of congenital syphilis, pointing to the urgent need for antenatal screening.
  • The study identified significant associations between congenital syphilis and risk factors, including HIV-positive status and vaginal discharge.
  • Deficiencies in antenatal syphilis screening were noted, with 28.5% of women not tested during pregnancy, emphasizing areas for improvement.

Cite This Study

Hamboote et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef72b87ece8dc957ab8https://doi.org/10.37432/jieph-confpro4-00002
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characteristics of Neonatal Congenital Syphilis at the University Teaching Hospital Children Division, Lusaka, Zambia: Pilot Study2025 · 1 citations
  2. 2Low syphilis treatment rates and associated birth outcomes in pregnant women with and without <scp>HIV</scp> in Zambia: A cohort study2025 · 1 citations
  3. 3Benzathine penicillin G stockouts and other barriers to documented syphilis treatment in pregnancy in Zambia2024 · 5 citations
  4. 4Resurgence of congenital syphilis: A profile of symptomatic newborns with congenital syphilis requiring admission to the nursery at a peri-urban regional hospital in KwaZulu-Natal Province, South Africa2024 · 1 citations
  5. 5Prevalence of syphilis and associated factors among pregnant people attending antenatal care at public hospitals in Eastern Tigray, Ethiopia, an institutional based cross-sectional study2026