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September 5, 2025Chemical ScienceOpen Access

Sequence-Activated Near-Infrared Fluorescence Probe for Precisely Tracking in Vivo Senescence

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Real-time monitoring of senescent cells is achieved using a near-infrared fluorescence probe, enhancing our understanding of aging.
The study identifies how the probe can precisely track senescent cells, as traditional methods are not unique and can lead to false positives.
Using innovative near-infrared fluorescence technology allows for significant improvements in monitoring cellular senescence in vivo, especially with aging-related interventions.
These findings may enable better strategies for understanding aging processes and developing interventions for age-related diseases.

Implication

This research demonstrates real-time monitoring of senescent cells in vivo, suggesting significant implications for aging studies.

Abstract

Real-time monitoring of senescent cells is of great significance for understanding and intervening in aging. Since overexpression of endogenous β-galactosidase (β-gal) is not unique to senescent cells, the probes relying...

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Cite This Study

Nong et al. (2025) studied this question.

synapsesocial.com/papers/68bb420d2b87ece8dc95803f https://doi.org/10.1039/d5sc05331e

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Implication

This research demonstrates real-time monitoring of senescent cells in vivo, suggesting significant implications for aging studies.

Sequence-Activated Near-Infrared Fluorescence Probe for Precisely Tracking in Vivo Senescence

Key Points

Implication

Abstract

Discussion

Cite This Study

Sequence-Activated Near-Infrared Fluorescence Probe for Precisely Tracking in Vivo Senescence

Key Points

Implication

Abstract

Discussion

Cite This Study

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