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This is a Literature Review study.

Neuroendocrine Effects of Hyperprolactinemia: Focus on Dopamine and Serotonin Systems

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This review explores hyperprolactinemia's effects on dopamine and serotonin, revealing links to mood disorders.

High prolactin levels disrupt dopaminergic signaling, which can lead to neuropsychiatric disorders.
Elevated prolactin has been found to negatively impact the serotonergic system, worsening symptoms of mood disturbances.
The review evaluates interactions between prolactin and neurotransmitter systems, highlighting significant neuropsychiatric implications.
Dopamine agonists are explored as potential treatment strategies for addressing neurotransmitter imbalances linked to hyperprolactinemia.

Kadiri et al. (2025) studied this question.

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