Randomised control trial assesses oral care's effectiveness in cutting hospital-acquired pneumonia rates, suggesting improved care may enhance outcomes.
The Hospital-acquired Pneumonia Prevention (HAPPEN) study is a multi-site, stepped wedge cluster randomised trial evaluating the impacts of improving oral care among adult patients to reduce the incidence of non-ventilator, hospital-acquired pneumonia (HAP). This document is the Health Economics Analysis Plan (HEAP) for evaluating the cost-effectiveness of the intervention compared with usual care. The trial was preregistered on the Australian and New Zealand Clinical Trials registry (ACTRN12624000187549) and is funded by the Medical Research Future Fund (MRF2022645). A copy of the study protocol and a signed version of this plan are available on request from the corresponding author (BM) .
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Sharma et al. (2025) studied this question.
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