Photoredox catalysis improves cyclopentene production from γ-alkynyl β-sulfonyl esters, suggesting efficiency in organic synthesis.
A visible-light-driven regioselective intramolecular cyclization and oxidation cascade of γ-alkynyl β-sulfonylester is developed. This metal-free approach efficiently affords synthetically useful cyclopentene and cyclohexene skeletons under mild conditions, with TEMPO acting as a dual electron and oxygen atom donor. Mechanism investigations support a radical cyclization/TEMPO-trapping cascade.
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Jiang et al. (2025) studied this question.
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