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September 5, 2025Toxicology Mechanisms and Methods

Investigating the Mechanism of Phthalates in Breast Cancer Using Molecular Docking and Network Toxicology

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Authors

JZJinrui ZhangWZWenjie ZhangLZLei Zhang

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Overview

Investigation reveals significant interactions with breast cancer pathways, suggesting potential risks from phthalates.

Key Points

  • The study found six pivotal molecular targets and their roles in breast cancer pathways, suggesting potential risks from phthalates.
  • Essential targets identified include EP300, CYCS, MTOR, and PPARγ, with implications for environmental monitoring.
  • Analysis employed molecular docking and network toxicology, yielding insights into phthalates' effects on breast cancer.
  • Highlights the connection between phthalates and the KSHV infection pathway, indicating additional cancer-related concerns.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68bb421a2b87ece8dc958972https://doi.org/10.1080/15376516.2025.2553099
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