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September 5, 2025Frontiers in MicrobiologyOpen Access

Identification of nasopharyngeal microbial dysbiosis in COVID-19 patients by 16S rRNA gene sequencing

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Authors

FKFilippos S. KardarasESEirini SiatravaniKTKaterina Tsilipounidaki

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Overview

This study identifies distinct nasopharyngeal microbiome profiles in COVID-19 patients, suggesting relevant microbial changes during infection.

Key Points

  • Distinct nasopharyngeal microbial profiles correlate with COVID-19 severity, indicating potential diagnostic value.
  • Alpha diversity declines significantly in severe COVID-19 cases, with notable differences in microbial composition across groups.
  • Microbiome profiling using 16S rRNA gene sequencing revealed variations in key microbial families linked to disease progression.
  • Increased abundance of pathogenic bacteria is observed in severe cases, suggesting a role in the dynamics of COVID-19 infection.

Cite This Study

Kardaras et al. (2025) studied this question.

synapsesocial.com/papers/68bb42212b87ece8dc958a3bhttps://doi.org/10.3389/fmicb.2025.1631198
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