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September 5, 2025BMC PediatricsOpen Access

Association of early hyperglycemia with morbidity and mortality in very low birth weight infants

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Retrospective study reveals hyperglycemia increases morbidity in very low birth weight infants, indicating crucial need for monitoring.

Hyperglycemia significantly increases the risk of retinopathy of prematurity and intraventricular hemorrhage in very low birth weight infants.
Analysis of 255 infants showed that 44.7% had hyperglycemia, with significantly higher incidences of ROP and IVH compared to normoglycemic infants.
Logistic regression identified prolonged hyperglycemia and severe hyperglycemia as key factors for increased morbidity, reinforcing the need for careful monitoring.
Strict glucose monitoring and timely intervention are vital to mitigate complications in very low birth weight infants, particularly regarding ROP and IVH risks.

Zhu et al. (2025) studied this question.

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