Association of Various Factors with Restless Leg Syndrome in Patients of Chronic Kidney Disease

Objective: To explore the association of anemia, stage of chronic kidney disease, diabetes mellitus, age of the patient, and duration of chronic kidney disease/hemodialysis with restless leg syndrome in patients of chronic kidney disease. Study Design: Cross-sectional study Place and Duration of Study : Combined Military Hospital Sialkot, Pakistan from Jun to Dec 2022. Methodology: A total of 250 patients were included in the study. Sampling was done using the nonprobability consecutive sampling technique. Patients’ clinical evaluation was done for restless leg syndrome. Results: Out of 250 patients, 176(70.4%) were males and 74(29.6%) were females with a mean age of 47.6±12 years. Restless leg syndrome was observed in 82(32.8%) patients with chronic kidney disease. The 59(72.0%) males and 23(28.0%) females had restless leg syndrome. No significant difference among gender, smoking, BMI, alcohol consumption, and restless leg syndrome was observed. Significant difference among age groups, diabetes, anemia, duration, and stages of chronic kidney disease with p-value <0.001 was observed. Conclusions: Restless leg syndrome is prevalent in chronic kidney disease patients and is associated with anemia, stage of chronic kidney disease, duration of chronic kidney disease, diabetes mellitus, and age of the patient.