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September 5, 2025Proceedings of the National Academy of Sciences of Belarus Medical seriesOpen Access

Pathogenetic and clinical aspects of antibody formation to glutathione peroxidase in systemic lupus erythematosus

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Authors

OEOlga V. EmelyanovaMoscow Institute of Physics and Technology АТА. С. ТрофименкоVolgograd Institute of Business ОРО. А. РусановаVolgograd State Medical University

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Implication

Observational study evaluates antibody levels and enzyme activity in patients with systemic lupus erythematosus, indicating potential biomarkers for disease activity.

Key Points

A statistically significant increase in antibodies to glutathione peroxidase was observed in patients with systemic lupus erythematosus.
Participants with active systemic lupus erythematosus showed markedly lower enzyme activity compared to controls, suggesting a strong association.
The research highlighted that treatment correlated with normalized enzyme activity and reduced antibody levels, which could inform clinical management.
These findings support the potential of using plasma glutathione peroxidase activity and antibody levels as biomarkers for assessing disease activity in systemic lupus erythematosus.

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Emelyanova et al. (2025) studied this question.

synapsesocial.com/papers/68bb46c36d6d5674bccfedb1 https://doi.org/10.29235/1814-6023-2025-22-3-232-238

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Implication

Observational study evaluates antibody levels and enzyme activity in patients with systemic lupus erythematosus, indicating potential biomarkers for disease activity.

Pathogenetic and clinical aspects of antibody formation to glutathione peroxidase in systemic lupus erythematosus

Discussion

Member takes

Implication

Key Points

Cite This Study

Pathogenetic and clinical aspects of antibody formation to glutathione peroxidase in systemic lupus erythematosus

Discussion

Member takes

Implication

Key Points

Cite This Study

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