The Landscape of Clinical Genetics in Honduras, Central America

In Honduras, clinical genetics is still at an early stage of development despite the countrys rich genetic diversity and important research contributions from isolated academic groups. Distinct populations, such as Indigenous communities and the Afro-descendant Garifuna, illustrate unique genetic profiles and founder effects with direct public health relevance. However, the practice of clinical genetics in Honduras faces major barriers, including the absence of nationally trained specialists, limited diagnostic capacity, lack of neonatal screening legislation, and the absence of registries for genetic diseases. Recent initiatives, including civil society advocacy and the planned COCINH LAB-Honduras project, signal opportunities to advance diagnostics, research, and training. To fully realize this potential, Honduras must invest in human resources, establish legal and ethical frameworks, and foster regional and international collaborations. Strengthening clinical genetics is essential for Honduras to address its populations health needs and to ensure equitable access to modern genomic medicine.