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September 5, 2025Frontiers in PsychiatryOpen Access

Psychedelic therapy: bridging neuroplasticity, phenomenology, and clinical outcomes

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Authors

RKRonit KishonColumbia University Irving Medical CenterYCYael M. CycowiczNew York Psychoanalytic Society and Institute

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Implication

Observational analysis highlights the therapeutic effects of psychedelic therapy on psychiatric disorders, suggesting neuroplastic benefits.

Key Points

  • Psychedelic therapy facilitates profound personal changes in self-perception and emotional regulation.
  • Current clinical trials evaluate pharmacological efficacy across diagnostic categories related to psychiatric disorders.
  • The therapy's three phases—preparation, administration, and integration—are essential for effective implementation.
  • Emerging evidence points to lasting therapeutic benefits beyond immediate symptom relief from psychedelic experiences.

Cite This Study

Kishon et al. (2025) studied this question.

synapsesocial.com/papers/68bb49bc6d6d5674bccff5d4https://doi.org/10.3389/fpsyt.2025.1637162
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Models of Psychedelic-Assisted Psychotherapy: A Contemporary Assessment and an Introduction to EMBARK, a Transdiagnostic, Trans-Drug Model2022 · 91 citations
  2. 2Psychedelic Treatments for Psychiatric Disorders: A Systematic Review and Thematic Synthesis of Patient Experiences in Qualitative Studies2020 · 225 citations
  3. 3The Emerging Field of Psychedelic Psychotherapy2022 · 57 citations
  4. 4Psychedelic resting-state neuroimaging: A review and perspective on balancing replication and novel analyses2022 · 120 citations
  5. 5Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial2016 · 1,748 citations