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September 5, 2025MedicinaOpen Access

Comparative Prognostic Role of PLR and NLR in Colon Cancer: A Retrospective Analysis of Preoperative Inflammatory Markers

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Retrospective analysis reveals PLR is more indicative of tumor aggressiveness in colon cancer patients.

PLR significantly correlates with tumor size and stage, indicating its potential as a prognostic marker.
Statistical analysis demonstrates that while PLR reflects tumor burden, NLR is associated with systemic inflammation.
Neither PLR nor NLR predicted postoperative complications or in-hospital mortality in colon cancer patients.
This retrospective cohort study highlights moderate associations between PLR and tumor characteristics, requiring further research.

Negruț et al. (2025) studied this question.

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