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September 5, 2025Physiological Entomology

The effect of inactivated bacteria on the redox status of larvae of the wax moth Galleria mellonella

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Authors

YVYana L. VorontsovaInstitute of Systematics and Ecology of AnimalsISIrina A. SlepnevaInstitute of Chemical Kinetics and CombustionNKNatalia A. KryukovaInstitute of Systematics and Ecology of Animals

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Overview

Experiments reveal inactivated Bacillus species modulate immune responses in Galleria mellonella, suggesting altered oxidative stress.

Key Points

  • Inactivated Bacillus spp. significantly modulates immune responses in wax moth larvae, enhancing immunocompetent haemocytes.
  • Exposure to Bacillus thuringiensis inhibits phenoloxidase activity and reduces reactive oxygen species in haemolymph.
  • The antioxidant response to bacterial inoculation in larvae differs between midgut and haemolymph, indicating a complex defense mechanism.
  • This study highlights the unique interactions between inactivated bacteria and the oxidative stress responses in Galleria mellonella.

Cite This Study

Vorontsova et al. (2025) studied this question.

synapsesocial.com/papers/68bb49d26d6d5674bccfff6ahttps://doi.org/10.1111/phen.70004
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