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September 5, 2025Journal of Infection and Public HealthOpen Access

Beyond Neutropenia: 14 Years Analysis of bloodstream infections in Hematological malignancies.

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Authors

AKAiah M. KhatebABAhmed S. BarefahOROsman Radhwi

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Overview

Retrospective study on bloodstream infections noted high resistance patterns and mortality in hematological malignancies, indicating urgent need for optimized management.

Key Points

  • Fourteen percent of patients with hematological malignancies experienced bloodstream infections, indicating a significant clinical challenge.
  • Among 2,112 patients, bacterial infections were predominant, accounting for 90%, with Gram-negative bacteria such as E. coli being notably high.
  • Statistical analysis revealed concerning resistance patterns, especially in Klebsiella pneumoniae, where mortality reached 100% for resistant strains.
  • Improved diagnostic strategies using both aerobic and anaerobic cultures enhanced identification of polymicrobial infections, suggesting better management potential.

Cite This Study

Khateb et al. (2025) studied this question.

synapsesocial.com/papers/68bb4d196d6d5674bcd00b3chttps://doi.org/10.1016/j.jiph.2025.102948
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Etiology, antimicrobial resistance, and outcomes of bloodstream infection in neutropenic hematological patients2026
  2. 2Evaluation of bloodstream infections in febrile neutropenic patients with hematological malignancy: a retrospective cohort study.2026 · 1 citations
  3. 3Evaluation of Enterobacterales bloodstream ınfections in hematologic cancer patients2024
  4. 4Bloodstream Infections In Cancer Patients In Central India: Pathogens And Trends Of Antimicrobial Resistance Over A Five-Year Period.2024
  5. 5Microbiological profile and antimicrobial susceptibility patterns of blood stream infections in febrile neutropenic patients with hematological malignancies in a tertiary care hospital, Kolkata2024