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September 5, 2025npj Biofilms and MicrobiomesOpen Access

Enteroendocrine cells: the gatekeepers of microbiome-gut-brain communication

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Authors

EGEsmée GrundekenSASahar El Aidy

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Overview

This review highlights roles of enteroendocrine cells in gut-brain communication and disease pathways, suggesting future research directions.

Key Points

  • Enteroendocrine cells play a crucial role in influencing gut-brain communication and overall health.
  • The review identifies significant research gaps in understanding enteroendocrine cells' interactions with the microbiome and diet.
  • Understanding the functions of enteroendocrine cells can provide insights into systemic signalling and disease pathways.
  • Future studies are needed to explore the underexplored connections between enteroendocrine cells and microbiome interactions.

Cite This Study

Grundeken et al. (2025) studied this question.

synapsesocial.com/papers/68bb4d196d6d5674bcd00b95https://doi.org/10.1038/s41522-025-00810-x
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