Case-control analysis reveals significant associations between AGER genetic variants and COPD susceptibility, suggesting a role in disease pathogenesis.
Objective Chronic obstructive pulmonary disease (COPD) remains a leading cause of disability and mortality among elderly populations. Studies indicate that AGER plays a critical regulatory role in the pathogenesis of respiratory disorders. However, the genetic variations in AGER to COPD susceptibility remain incompletely understood. This study employs a case–control design to investigate associations between AGER genetic variants and COPD risk in the Southern Chinese Han population.
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Xie et al. (2025) studied this question.
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