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Combined kinetic and computational investigation shows cyclodextrins stabilize 5-fluorouracil across pH levels, indicating significant protective effects.
The photostabilization of 5-fluorouracil (5-FU) has been carried out in the pH range of 2.0–12.0 using cyclodextrins (α-, β-, γ-) as a complexing agent.
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Khurshid et al. (2025) studied this question.
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