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September 5, 2025Bulletin of the National Research Centre/Bulletin of the National Research CenterOpen Access

The efficacy of ‘ready-to-use therapeutic food - RUTF’ without milk to modulate severe acute malnutrition (SAM) in low- and middle-income countries (LMICs): a scoping review

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Authors

FDFrancis DansoITIhab Tewfik

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Overview

Scoping review shows non-milk RUTF achieves comparable outcomes in SAM cases across LMICs, indicating its potential as a cost-effective alternative.

Key Points

  • Non-milk RUTF produced comparable weight gain to standard RUTF, showing promise for SAM treatment.
  • Recovery rates for non-milk RUTF ranged from 54 to 90%, suggesting its effectiveness in children with SAM.
  • Haemoglobin levels improved significantly in anaemic children treated with non-milk RUTF, enhancing iron status.
  • Mortality and morbidity rates were similar between non-milk RUTF and standard RUTF, supporting its viability.

Cite This Study

Danso et al. (2025) studied this question.

synapsesocial.com/papers/68bb4de86d6d5674bcd019cbhttps://doi.org/10.1186/s42269-025-01355-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment outcome and associated factors for severely malnourished children (1–5 years) admitted to Lacor Hospital and Gulu Regional Referral Hospital in Uganda2021 · 13 citations
  2. 2Ready-to-Use Therapeutic Foods (RUTFs) Based on Local Recipes Are as Efficacious and Have a Higher Acceptability than a Standard Peanut-Based RUTF: A Randomized Controlled Trial in Indonesia2023 · 14 citations
  3. 3Severe Acute Malnutrition: The Potential of Non-Peanut, Non-Milk Ready-to-Use Therapeutic Foods2023 · 12 citations
  4. 4Ready-to-use therapeutic food (RUTF) for home-based nutritional rehabilitation of severe acute malnutrition in children from six months to five years of age2019 · 99 citations
  5. 5Alternative Ready-To-Use Therapeutic Food Yields Less Recovery Than the Standard for Treating Acute Malnutrition in Children From Ghana2019 · 41 citations