Interplay of Spatial Structure and Population Interactions in Microbial Communities

Given that most microbes experience spatially structured environments, examining how such environments affect microbial growth and functions is paramount. Previous studies have shown that a spatially structured environment can impact microbial growth and interactions, and that microbial growth can create or magnify spatial structure. Here, we review some of these instances of past studies to develop a consistent framework that highlights the interplay between microbial interactions, spatial structure of the environment, and spatial organization of microbes. We discuss how mathematical models can reveal the contribution of the spatial structure to community assembly and coexistence. Lastly, we offer an outlook of important steps for the progress of this field.