From Lab to Field: Harnessing H₂O₂‐Mediated Upregulation of Plant Capacities Under Abiotic Stresses

Climate‐driven abiotic stresses, responsible for approximately 50% of global crop yield losses, are putting agriculture under increasing pressure, demanding smarter ways to strengthen plants' natural defenses beyond genetic modification. Hydrogen peroxide (H 2 O 2 ), long recognized as a key signaling molecule, plays a powerful role in helping plants cope with environmental stress. This review deciphers the mechanistic basis of H 2 O 2 ‐mediated capacity enhancement under diverse stresses (drought, salinity, heavy metals, heat, cold) while also addressing climate‐intensified challenges like waterlogging and ultraviolet (UV) radiation. We spotlight its roles in energy partitioning, hormonal signaling, asset optimization, and internal supply chain dynamics, positioning H 2 O 2 as a multifunctional coordinator of stress resilience. Moving beyond the antioxidant narrative, this review highlights the active role of H 2 O 2 in reorganizing plant responses to real‐world stress. Can a molecule once known only for causing damage now lead the next wave of environmentally friendly, stress‐resilient agriculture? We propose that H 2 O 2 ‐based strategies represent a promising shift toward redox‐guided, non‐genetic interventions bridging laboratory research with practical field applications and opening new pathways for resilient crop management.