What type of study is this?

This is a Systematic Review study.

September 5, 2025Frontiers in NeurologyOpen Access

Riboflavin in neurological diseases: therapeutic advances, metabolic insights, and emerging genetic strategies

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This review analyzes riboflavin's therapeutic applications and metabolic roles in neurological diseases, suggesting new gene-based strategies.

Riboflavin supplementation, particularly at high doses, has shown significant efficacy in neurological conditions.
Conditions like riboflavin transporter deficiency and multiple acyl-CoA dehydrogenase deficiency benefit from riboflavin.
Mitochondrial function and antioxidant systems are supported by riboflavin, highlighting its importance in neurological health.
Advancements in gene therapy targeting riboflavin-related pathways present novel therapeutic opportunities.

Tao et al. (2025) studied this question.

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This review analyzes riboflavin's therapeutic applications and metabolic roles in neurological diseases, suggesting new gene-based strategies.