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September 5, 2025Journal of Veterinary Internal MedicineOpen Access

A Multicenter, Retrospective Analysis of Long‐Term Survival in 255 Dogs With Pheochromocytoma Treated With Alpha‐Adrenoreceptor Antagonists or Surgery (2010–2021)

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Authors

MSMatthew M. E. SteeleWillows Veterinary Centre and Referral Service MBMarit F. van den BergUtrecht University SGSara GalacUniversity of Applied Sciences Utrecht

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Implication

Retrospective analysis compares survival of dogs with pheochromocytoma receiving surgery or adrenoreceptor antagonists, indicating better outcomes for surgical cases.

Key Points

Dogs with pheochromocytoma treated with adrenalectomy showed significantly longer survival compared to those treated with adrenoreceptor antagonists.
Median overall survival time was 854 days, with surgically treated dogs surviving a median of 927 days versus 247 days for medical management.
The analysis utilized statistical methods like Kaplan–Meier estimates and Cox proportional hazard analysis to evaluate survival factors.
Findings suggest that clinical signs at presentation can impact survival rates, emphasizing the importance of early diagnosis.

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Steele et al. (2025) studied this question.

synapsesocial.com/papers/68bb4dfb6d6d5674bcd0250e https://doi.org/10.1111/jvim.70220

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Implication

Retrospective analysis compares survival of dogs with pheochromocytoma receiving surgery or adrenoreceptor antagonists, indicating better outcomes for surgical cases.

A Multicenter, Retrospective Analysis of Long‐Term Survival in 255 Dogs With Pheochromocytoma Treated With Alpha‐Adrenoreceptor Antagonists or Surgery (2010–2021)

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Key Points

Cite This Study

A Multicenter, Retrospective Analysis of Long‐Term Survival in 255 Dogs With Pheochromocytoma Treated With Alpha‐Adrenoreceptor Antagonists or Surgery (2010–2021)

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