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September 5, 2025Open Access

Prognostic analysis of immunomarkers for non-small cell lung cancer

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Authors

XWXinmei WangZhejiang Normal UniversityZYZhi-Qiong YuYangtze UniversityWHWeihua HuGanzhou People's Hospital

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Overview

Retrospective analysis shows PD-L1 correlates with tumor size in NSCLC, suggesting prognostic utility.

Key Points

  • Higher PD-L1 expression correlates with increased tumor size, and CD8 + TILs correlate with lymph node metastasis.
  • Survival analysis indicates longer PFS of 15 months in CD4 + TILs low infiltration patients compared to 6 months in high infiltration.
  • Multifactorial Cox regression highlights PD-L1 high expression and lung adenocarcinoma as independent risk factors for PFS.
  • Combined assessment of PD-L1 and immune infiltration traits may guide individualized immunotherapy strategies.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd026cbhttps://doi.org/10.21203/rs.3.rs-7042926/v1
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