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September 2, 2025Open Access

Figure S2 from Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type 1 Dendritic Cells for Cancer Immunotherapy Applications

Sreekumar Balan Liam O’Brien Ante Peros Xuedi Wang Ingrid Leal Rojas Christopher B. McClain Kristen J. Radford Nina Bhardwaj

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Key Points

Enhanced functionality of dendritic cells can improve outcomes in cancer immunotherapy.
Key findings include the expression of DC associated and lineage markers on differentiated cells.
The approach involves in vitro differentiation of dendritic cells from various cultures.
These results may highlight the potential of notch signaling in therapeutic applications.

Implication

Observational analysis shows improved functionality of dendritic cells with notch signaling, suggesting new cancer immunotherapy strategies.

Abstract

Expression of DC associated and lineage markers on in vitro differentiated cells from different cultures

Discussion

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Cite This Study

Balan et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd0288f https://doi.org/10.1158/2326-6066.30028885

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type 1 Dendritic Cells for Cancer Immunotherapy Applications2025
2Figure S4 from Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type 1 Dendritic Cells for Cancer Immunotherapy Applications2025
3Figure S5 from Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type 1 Dendritic Cells for Cancer Immunotherapy Applications2025
4Figure S1 from Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type 1 Dendritic Cells for Cancer Immunotherapy Applications2025
5Figure S6 from Harnessing Notch Signaling to Enhance the Generation and Functionality of Human Conventional Type 1 Dendritic Cells for Cancer Immunotherapy Applications2025

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