Can the Systemic Immune-Inflammation Index (SII) Predict the Outcome of Threatened Miscarriage?

Yıldız Akdaş Reis; Fahri Burçin Fıratlıgil; Arife Akay; Serap Topkara Sucu; Seval Yılmaz Ergani; Sadullah Özkan; Salim Erkaya; Yaprak Engin Üstün

doi:10.20492/aeahtd.1552571

August 29, 2025Ankara Eğitim ve Araştırma Hastanesi Tıp DergisiOpen Access

Can the Systemic Immune-Inflammation Index (SII) Predict the Outcome of Threatened Miscarriage?

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Key Points

Systemic immune-inflammation index was statistically significantly higher in women who gave birth compared to those who miscarried.
In a study of 730 singleton pregnant women with threatened miscarriage, 239 had miscarriages while 491 had successful childbirth.
Receiver operating characteristic curves were utilized to assess the predictive performance of inflammatory biomarkers for outcomes in threatened miscarriage.
The findings highlight the need for reliable biomarkers to improve pregnancy outcome predictions, with SII being a promising candidate.

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Implication

Retrospective case-control study finds systemic immune-inflammation index may predict outcomes in threatened miscarriage, suggesting potential clinical utility.

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Cite This Study

Reis et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f266d6d5674bcd030dd https://doi.org/10.20492/aeahtd.1552571

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Can the Systemic Immune-Inflammation Index (SII) Predict the Outcome of Threatened Miscarriage?

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Can the Systemic Immune-Inflammation Index (SII) Predict the Outcome of Threatened Miscarriage?

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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