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The diagnostic value and clinical relevance of salivary gland ultrasound in patients with highly suspected Sjögren’s Disease: a prospective monocentric study

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This study assesses the diagnostic accuracy of salivary gland ultrasound in Sjögren's Disease, suggesting potential clinical relevance.

The salivary gland ultrasound demonstrated moderate efficacy in diagnosing Sjögren's Disease, with an AUC of 0.78.
Specificity reached 93% with salivary gland ultrasound, while sensitivity was lower at 52%, indicating varied diagnostic capabilities.
Combining salivary gland ultrasound with labial salivary gland biopsy improved diagnostic performance, achieving a specificity of 100%.
Grade 3 ultrasound findings significantly correlated with positive biopsy results, emphasizing its potential role in diagnosis.

Shi et al. (2025) studied this question.

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