Pilot randomized cross-over study shows NMES increases lactate and IGF-1 in spinal cord injury, suggesting cognitive benefits.
Introduction: Individuals with spinal cord injuries (SCI) exhibit an accelerated age-related cognitive decline compared to healthy individuals, even after adjusting for mood factors and concomitant traumatic brain injury. We hypothesized that neuromuscular electrical stimulation (NMES) on hamstring and gluteal muscles may induce a dose-dependent increase in lactate and insulin-like growth factor-1 (IGF-1) which is hypothesized to be associated with a temporary enhancement of cognitive performance.
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Vints et al. (2025) studied this question.
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