This review highlights artificial peptide inducers and inhibitors of autophagy, suggesting a new therapeutic approach.
Autophagy is a highly conserved lysosomal degradation pathway for maintaining cellular homeostasis. Its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections, making precise modulation of autophagy a potentially promising therapeutic strategy. Artificial peptide‐based autophagy modulators have emerged as a promising alternative to conventional small molecules, offering several advantages in terms of specificity, biocompatibility, and functional versatility. This review summarizes recent advances in artificial peptide‐based autophagy monitoring tools, autophagy inducers, and autophagy inhibitors.
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Cai et al. (2025) studied this question.
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