Case report reveals synchronous papillary and follicular thyroid carcinoma, highlighting diagnostic challenges.
Rationale: Collision tumors involving differentiated thyroid carcinomas are exceedingly rare, despite the overall high prevalence of thyroid cancer. Patient concerns: A 65-year-old man was incidentally diagnosed with thyroid cancer during a staging workup for gastric cancer. Diagnoses: The histopathologic examination revealed 2 coincident cancers of the left thyroid lobe: papillary carcinoma (pT1bN1a) and follicular carcinoma (pT2N0). Interventions: The patient underwent total thyroidectomy with central lymph node dissection, followed by thyroid hormone suppression and radioactive iodine therapy. Outcomes: No postoperative complications or cancer recurrence has been observed to date. Lessons: This case highlights the diagnostic challenges and surgical considerations associated with collision tumors of the thyroid. Appropriate management remains controversial; therefore, further case studies and consensus guidelines are necessary.
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Kim et al. (2025) studied this question.
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