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September 1, 2025International Journal of Infectious DiseasesOpen Access

Diagnostic Accuracy of a Host Response Test in Suspected Community-Acquired Pneumonia During the COVID-19 Era

Christina Skår Saghaug Dagfinn Lunde Markussen Siri Tandberg Knoop Benedicte C Holvik Sondre Serigstad Elling Ulvestad Christian Ritz Synne Jenum Harleen M. S. Grewal

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Key Points

MeMed BV® test showed a positive percent agreement of 90% for bacterial infections, indicating high sensitivity.
Among 370 patients, the negative percent agreement was 30.1%, highlighting limited specificity for viral infections.
Testing classified patients using clinical management and molecular detection, ensuring robust diagnostic evaluation.
Study findings suggest MeMed BV® may assist early triage in pneumonia cases, combined with clinical data.

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Implication

Prospective analysis demonstrated high sensitivity in detecting bacterial pneumonia, suggesting implications for diagnostic uncertainty.

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Cite This Study

Saghaug et al. (2025) studied this question.

synapsesocial.com/papers/68c1824b9b7b07f3a060ea12 https://doi.org/10.1016/j.ijid.2025.108045

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