Comprehensive review explores extracellular vesicles' benefits in cosmetics, highlighting regulatory challenges and market trends.
Extracellular vesicles (EVs) have gained attention in the cosmetics industry for their role in intercellular communication and tissue regeneration. They transfer bioactive molecules such as proteins, lipids, and nucleic acids, promoting skin repair, rejuvenation, and anti-aging effects. Human mesenchymal stem cell-derived EVs are particularly valued for their ability to enhance collagen production, reduce inflammation, and improve skin texture and hydration. However, their use is prohibited by regulatory agencies. Plant- and bacterial-derived EVs are being explored to meet the demand for innovative cosmetics. Despite their potential, challenges such as regulatory approval, high production costs, and product stability need to be addressed to fully realize the benefits of EV-based cosmetics. This paper examines the mechanisms, benefits, market trends, and prospects of EV-based skincare products, highlighting their transformative impact on the cosmetic industry.
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Col et al. (2025) studied this question.
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