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September 10, 2025Frontiers in NutritionOpen Access

Constipation symptoms are associated with worse cognitive outcomes in older adults without dementia

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Constipation is associated with a higher risk of mild cognitive impairment, especially in language and executive function.
Participants diagnosed with constipation showed 20.1% prevalence, with specific symptoms increasing the odds of cognitive impairment.
Multivariate logistic regression analysis revealed critical odds ratios for various cognitive impairments linked to constipation symptoms.
Depressive symptoms acted as a mediator in the association of constipation with cognitive functions, highlighting the need for further research.

Authors

XLXiaochang LiuChinese Academy of Agricultural Sciences JZJuan ZhouEast China Jiaotong University XXXinyan XieChongqing Three Gorges University

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Implication

Observational analysis shows higher mild cognitive impairment risk in older adults with constipation, suggesting a potential link with depressive symptoms.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c187179b7b07f3a0610d8f https://doi.org/10.3389/fnut.2025.1578181

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Implication

Observational analysis shows higher mild cognitive impairment risk in older adults with constipation, suggesting a potential link with depressive symptoms.

Constipation symptoms are associated with worse cognitive outcomes in older adults without dementia

Key Points

Discussion

Implication

Cite This Study

Constipation symptoms are associated with worse cognitive outcomes in older adults without dementia

Key Points

Discussion

Implication

Cite This Study

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