"Dietary Supplementation Improves Markers of Inflammation, Oxidative Stress, and Endothelial Function in a Healthy Adults."

Objectives: This study is to investigate the effects of 3 functional food supplements on basic metabolic parameters on 61 healthy adult individuals. The 24-week study was completed with 43 men and 18 adult women. The average age of the participants was 30 ± 9 years. Methods: In this study, anti-atherosclerotic liquid (AAL)-Morinda citrifolia (3 mL once per day orally) anti-inflammatory capsules (AIC)-Omega-3 (3 capsules once per day orally) extract with antioxidant liquid (AOL)- Blueberry and 21 different red purple fruit vegetables (30 mL once per day orally) have been used. We compared 24 weeks before and after. Results: The study shows the longitudinal changes of selected parameters in the 61 healthy people that completed the study. Following anti-atherosclerotic liquid (AAL), anti-inflammatory capsules (AIC) and antioxidant liquid (AOL) therapies, asymmetric dimethylarginine (ADMA), malondialdehyde (MDA), pentraxin-3 (PTX3), homeostatic model assessment of insulin resistance (HOMA-IR), high-sensitivity C-reactive protein (hs-CRP), systolic blood pressure (SBP), diastolic blood pressure (DBP), glycated hemoglobin (HbA1c), body mass index (BMI), fasting plasma glucose (FPG), total cholesterol, and low-density lipoprotein cholesterol (LDL) levels were significantly decreased, while flow-mediated dilation (FMD), glutathione peroxidase (GSH-Px), high-density lipoprotein cholesterol (HDL), 25-hydroxyvitamin D (25OHVD), and folic acid levels were significantly increased. Conclusions: Our results indicated that selected functional food supplements showed strong beneficial effect on selected metabolic parameters.