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Implantable Medical Devices, Biomaterials, and the Foreign Body Response: A Surgical Perspective

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The foreign body response can lead to inflammation and fibrous encapsulation, affecting device function.
Dysregulation of the immune response can cause patient morbidity and device failure, necessitating revision surgery.
Factors influencing the foreign body response include biomaterial properties, host characteristics, and surgical techniques.
Strategies for managing the foreign body response aim to reduce complications during the implantation process.

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Review analyzes the foreign body response and its effect on implantable medical devices, suggesting surgical control methods.

Kalashnikov et al. (2025) studied this question.

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