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January 1, 2025Analytical Methods

Ecofriendly Densitometric (RP and NP) HPTLC Methods for Determination of Sorafenib in bulk and formulation

Pratiksha P. Bang Hardik Bhatt

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Key Points

Ecofriendly densitometric methods provide precise quality control for sorafenib in pharmaceuticals.
These HPTLC methods enhance sustainability and efficiency in the analysis of anticancer drugs.
The study emphasizes the growing importance of green methodologies in pharmaceutical practices.
Densitometric techniques ensure high accuracy in determining sorafenib levels in bulk and formulations.

Implication

Densitometric techniques assess sorafenib in formulations, highlighting sustainable practices.

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Cite This Study

Bang et al. (2025) studied this question.

synapsesocial.com/papers/68c1872d9b7b07f3a06117fa https://doi.org/10.1039/d5ay01031d

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Green Analytical Approach for HPLC Method Development for Quantification of Sorafenib and Its Pharmacopeia Impurities: LC–MS/MS Characterization and Toxicity Prediction of Stress Degradation Products2024 · 6 citations
2Box-Behnken Design employed stability demonstrating RP-HPLC method development of sorafenib tosylate for rapid and sensitive quantification2024
3GREEN ANALYTICAL CHEMISTRY APPROACH IN RP-HPLC FOR QUANTITATIVE ESTIMATIONS OF TYROSINE KINASE INHIBITOROriginal Research · 2026
4Approaches to conducting a physiologically relevant test (PRT) in the study of medicines containing substance IIc of the BCS subclass using sorafenib as an example2024
5Green and sustainable RP-HPTLC method for simultaneous determination of doravirine and islatravir in bulk and pharmaceutical dosage form with comprehensive greenness assessmentOriginal Research · 2026

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DIFFUSE REFLECTANCE INFRARED FOURIER TRANSFORM SPECTROSCOPIC METHOD FOR ESTIMATION OF NERATINIB IN PHARMACEUTICALS: APPLICATION TO ANALYTICAL QUALITY BY DESIGN AND GREENNESS ASSESSMENT2024
Comparing the Greenness and Validation Metrics of Traditional and Eco-Friendly Stability-Indicating HPTLC Methods for Ertugliflozin Determination2024
Eco-conscious AQbD-guided stability-indicating RP-UPLC method for analysing Tovorafenib in bulk and dosage forms2025

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