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Supplementary figure shows effects of FOS-diet on tumor growth and T-cell counts in mice, suggesting potential impacts on car t therapy outcomes.
Supplementary Figure S13 investigates the effects of a FOS-diet on CAR T cells in an in vivo rechallenge model. The figure displays tumor growth monitored by bioluminescent imaging, shows absolute peripheral blood CD45+ T-cell counts post-tumor rechallenge, and includes a Kaplan-Meier survival curve for tumor-bearing mice treated with CAR T cells, with or without FOS feeding.
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Uribe‐Herranz et al. (2025) studied this question.
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