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September 10, 2025International Journal of experimental research and reviewOpen Access

Liraglutide-Metformin Combination Therapy in Type 2 Diabetes: A Comprehensive Review of Clinical Efficacy, Safety and Cost-Effectiveness

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Authors

ACAashish ChoudharySKSanjaikrishna Pakkirisamy KannanKPKamala Kanta Parhi

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Overview

Comprehensive review evaluates liraglutide and metformin in type 2 diabetes, highlighting efficacy and safety. It suggests cost-effectiveness compared to other second-line treatments.

Key Points

  • Liraglutide significantly improves glycemic control in type 2 diabetes while reducing risk of hypoglycemia.
  • Clinical trials show liraglutide offers cardioprotective effects, lowering major adverse cardiovascular events.
  • Economic models indicate liraglutide’s cost-effectiveness through reduced complications despite higher initial costs.
  • Patient satisfaction with liraglutide correlates with clinical efficacy, though real-world adherence varies widely.

Cite This Study

Choudhary et al. (2025) studied this question.

synapsesocial.com/papers/68c187339b7b07f3a0611bd3https://doi.org/10.52756/ijerr.2025.v48.007
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