Observational analysis reveals bias-adjusted correlation of AI-predicted ECG age with mortality and cardiovascular risk factors.
The gap between artificial intelligence (AI) derived ECG age and chronological age (Δage) has been correlated with cardiovascular risk factors and mortality. However, bias due to regression-towards-the-mean results in an age-Δage correlation which affects the relationship between Δage and these age-related variables.
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Barthels et al. (2025) studied this question.
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