Systematic review assesses ACTL6A's oncogenic impact and prognostic value in cancer, indicating significant implications for clinical outcomes.
Background Actin-like protein 6A (ACTL6A), a subunit of SWI/SNF (SWItch/Sucrose Non-Fermentable) complex has emerged as a key player in cancer progression. Despite growing evidence of its oncogenic potential, a comprehensive evaluation of its role in tumorigenesis and clinical outcomes remains warranted. This systematic review and meta-analysis aim to elucidate the role of ACTL6A in cancer pathophysiology and its prognostic significance.
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Patil et al. (2025) studied this question.
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