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September 10, 2025Canadian Geriatrics JournalOpen Access

A Description of QT-Interval Prolonging Drug Interactions with Fluoroquinolones in Older Women with Uncomplicated Urinary Tract Infections

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Retrospective cohort study identifies QT-interval prolonging drug interactions in older women, indicating potential TdP risk.

An increasing proportion of women on fluoroquinolones experienced QT-interval prolonging drug interactions.
Around 20.3% of drug interactions involved furosemide within 30 days of fluoroquinolone dispensation.
This observational study analyzed administrative health data from long-term care facilities for older women.
Prescribing fluoroquinolones requires monitoring to address modifiable risk factors for Torsades de Pointes.

Trenaman et al. (2025) studied this question.

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