The analysis highlights clinical practice implications and raises concerns about overdiagnosis and overtreatment.
The definition of disease is not a purely theoretical exercise but a choice with significant implications for clinical practice, public health, and resource management. The expansion of diagnostic criteria, aimed at reducing underdiagnosis, has led to an increase in overdiagnosis and overtreatment - critical issues still too little addressed in medical education and public communication.
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Fiore et al. (2025) studied this question.
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