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Supplemental analysis reveals associations between microbiota and T-cell exhaustion markers, indicating implications for CAR T-cell therapy in myeloma patients.
Supplementary Figure S9 characterizes the taxa and metabolites associated with T-cell exhaustion markers in the final CAR T-cell product from multiple myeloma patients. This figure specifically shows associations with both CD4+ T cells and CD8+ T cells, with negative associations indicated in blue and positive associations in red.
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Uribe‐Herranz et al. (2025) studied this question.
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