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Aminoglycoside Resistance in Common Pathogens

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Observational analysis reveals resistance trends in Escherichia coli and Pseudomonas aeruginosa, highlighting ICU impact.

Aminoglycoside resistance rates were notably higher in ICU isolates, particularly for gentamicin and amikacin, indicating a critical concern.
Isepamicin showed the lowest resistance among Gram-negative bacilli, suggesting its potential as a key treatment option for resistant infections.
Significant differences in aminoglycoside resistance were observed, particularly between strains isolated from ICU and non-ICU settings.
Routine susceptibility testing and careful antibiotic selection are crucial for managing resistance in high-risk populations such as ICU patients.

Durdu et al. (2025) studied this question.

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